Searchable abstracts of presentations at key conferences in endocrinology

ea0009oc21 | Oral Communication 3: Neuroendocrinology | BES2005

Adenosine expression and function in the anterior pituitary gland

Francis K , Pexa A , Lewis B , McNicol A , Jasani B , Deussen A , Scanlon M , Rees D , Ham J

The nucleoside adenosine is an important regulator of interleukin-6 secretion from the folliculostellate (FS) cells of the anterior pituitary gland but the source of adenosine in this scenario is unknown. Therefore the aim of this study was to investigate secretion of adenosine and the expression of adenosine forming and metabolising enzymes in the pituitary gland.Ecto-5/-nucleotidase (CD73), adenosine kinase and adenosine deaminase (AD) were ...